The genus contains a large variety of plants with differing features. Some have thick, waxy cuticles (as in A. lobbianus) others have much softer leaves (as in A. hildebrandii). Species such as A. speciosus are large where A. micranthus is much smaller and trailing. Several species are valued in temperate climates as houseplants, notably A. longicaulis, A. pulcher and A. radicans.

They require good lighting and semi-moist, well-drained soil conditions to grow, though they vary and some require more moist soil (such as A. hildebrandii). They also prefer warm and humid conditions. Aeschynanthus lobbianus needs high light intensity to induce flowering.

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